Name: Italian Penicillin Soup Recipe
Prep time: 10 min
Cook time: 45 min
Total time: 55 min
Cuisine: Italian
Ingredients: 8 cups lower-sodium chicken broth; 2 cups chopped sweet onion; 1 1/2 cups peeled and coarsely chopped carrots; 2 celery ribs, coarsely chopped; 6 garlic cloves, smashed and peeled; 3/4 teaspoon kosher salt; 4 thyme sprigs; 2 fresh bay leaves; 1 (2 ounce) Parmigiano-Reggiano cheese rind, plus grated cheese for garnish; 4 ounces uncooked pastina pasta; 2 cups shredded rotisserie chicken; Fresh flat-leaf parsley leaves

Jump to Recipe· 4.3 from 86 reviews

There is something truly special about a warm, hearty bowl that feels like a hug from the inside — and that is exactly what the Italian Penicillin Soup Recipe delivers. This comforting soup is a delicious twist on classic chicken noodle, featuring tender shredded rotisserie chicken, sweet vegetables, tiny pastina pasta, and the delightful richness of Parmesan cheese. Every spoonful offers a beautiful balance of flavors and textures that will have you savoring every bite and reaching for seconds. If you’re craving a soul-satisfying meal that’s both easy to make and packed with goodness, this Italian Penicillin Soup Recipe is about to become your new favorite.

Ingredients You'll Need

The image shows multiple clear glass bowls arranged on a white marbled surface. There is a large measuring cup filled with light golden broth on the right side. Surrounding it are smaller bowls containing chopped orange carrots, white chopped onions, finely chopped green celery, and shredded light beige cooked chicken. Small glass bowls hold white garlic cloves, white salt, yellow grated cheese, and a cinnamon stick. Fresh green parsley sprigs and a dried green bay leaf are also placed on the surface nearby. photo taken with an iphone --ar 4:5 --v 7

The magic of this Italian Penicillin Soup Recipe lies in its straightforward yet essential ingredients. Each one plays a key role in building layers of flavor, from the savory broth to the fresh herbs and creamy cheese rind. Simplicity here allows the natural tastes to shine and come together in perfect harmony.

8 cups lower-sodium chicken broth: The flavorful base that’s rich but not overpowering, crucial for the soup’s comforting essence.
2 cups chopped sweet onion: Adds a subtle sweetness and depth to the broth as it softens.
1 ½ cups peeled and coarsely chopped carrots: Provides natural sweetness and vibrant color that brightens every bowl.
2 celery ribs, coarsely chopped: Lends earthy aroma and a gentle crunch, balancing the vegetable medley.
6 garlic cloves, smashed and peeled: Garlic infuses the soup with warmth and a touch of pungency that elevates the overall flavor.
¾ teaspoon kosher salt: Enhances and sharpens the soup’s natural flavors while seasoning it perfectly.
4 thyme sprigs: Brings a subtle herbaceous note that complements the chicken and vegetables.
2 fresh bay leaves: Adds complexity and a slight woodsy background to the broth.
1 (2 ounce) Parmigiano-Reggiano cheese rind, plus grated cheese for garnish: Infuses the broth with that unforgettable umami punch and creamy richness.
4 ounces uncooked pastina pasta: Small, delicate pasta that cooks to tender perfection without overwhelming the soup.
2 cups shredded rotisserie chicken: Provides protein and a savory, juicy bite in every mouthful.
Fresh flat-leaf parsley leaves, for garnish: Adds a pop of fresh color and a mild herbaceous finish.

How to Make Italian Penicillin Soup Recipe

Step 1: Build the Broth and Soften Vegetables

Start by bringing your chicken broth, chopped onion, carrots, celery, garlic, and kosher salt to a robust boil in a large saucepan or small Dutch oven. The high heat quickly extracts flavors from the fresh ingredients. Then, lower the heat to medium-low and let everything simmer until the vegetables are tender, about 10 minutes. This gentle cooking melds the sweet onion and carrots with the savory broth, laying a flavorful foundation for the soup.

Step 2: Puree and Enrich the Soup Base

Using a slotted spoon, carefully transfer the softened vegetables and about one cup of broth to a blender. Secure the lid, and remove the center piece to allow steam to escape safely—cover the opening with a clean towel to avoid splatters. Blend for about 30 seconds until smooth, creating a luscious, velvety texture. Stir this vibrant carrot mixture back into the pot, giving the soup a silky mouthfeel and enhancing its natural sweetness.

Step 3: Infuse with Herbs and Cheese Rind

Add the thyme sprigs, bay leaves, and the Parmigiano-Reggiano cheese rind to your pot. Bring the soup back to a boil over medium-high heat to allow these ingredients to release their layers of flavor into the broth. The cheese rind is a secret hero here, delivering irresistible umami and creaminess. The herbs provide aromatic subtlety that ties everything together beautifully.

Step 4: Cook the Pasta and Add Chicken

Stir in the pastina pasta, then reduce the heat to medium-low and let the soup simmer gently, stirring occasionally. The pastina needs about 18 to 20 minutes to become perfectly tender without turning mushy. During the last three minutes, add the shredded rotisserie chicken so it warms through without drying out. This timing ensures the chicken stays juicy and the pasta remains delicate, creating a well-balanced texture throughout.

Step 5: Final Touches

Once the pasta is tender and the chicken heated, remove the soup from the heat. Carefully discard the thyme sprigs, bay leaves, and Parmigiano-Reggiano rind—they’ve done their work, infusing your soup with magnificent depth. Stir gently and get ready to serve.

How to Serve Italian Penicillin Soup Recipe

A round silver pot filled with thick yellow soup that has visible small shredded white pieces inside, likely chicken, is placed on a white marbled surface. A white stirring spoon with a small hole near the handle lies inside the pot, partially submerged in the soup. To the left of the pot, there is a small wooden tray holding a few dried herbs including a bay leaf, a small piece of dried fish or meat, and some thin dried leaves or roots, all resting on the same white marbled surface. photo taken with an iphone --ar 4:5 --v 7

Garnishes

A simple shower of freshly grated Parmigiano-Reggiano on top adds sparkling richness and a satisfyingly creamy finish to every spoonful. Don’t forget a sprinkle of fresh flat-leaf parsley leaves which brighten the soup with fresh color and a mild, herbaceous pop. These garnishes turn a humble bowl of soup into something truly special and inviting.

Side Dishes

This Italian Penicillin Soup Recipe pairs wonderfully with crusty bread or a rustic baguette to soak up that delicious broth. A crisp green salad with lemon vinaigrette can provide a refreshing contrast to the rich soup, making your meal more vibrant and satisfying. If you want to add a touch of indulgence, serve with roasted garlic focaccia or a light caprese salad for a complete Italian-inspired feast.

Creative Ways to Present

For a cozy dinner or entertaining friends, serve the soup in charming Italian-style ceramic bowls to amplify that authentic vibe. You can drizzle a bit of extra virgin olive oil or a few drops of chili oil on top to give a gourmet flair and a little heat. For an eye-catching presentation, try making individual servings in mini crockpots or ramekins, perfect for mezze-style gatherings or comforting winter suppers.

Make Ahead and Storage

Storing Leftovers

The Italian Penicillin Soup Recipe keeps beautifully in the fridge for up to three days. Store it in an airtight container to preserve freshness and aroma. Because the pastina pasta continues to absorb liquid, it may thicken when chilled, so you might want to add a splash of broth or water when reheating to restore that perfect soup consistency.

Freezing

You can freeze this soup for up to two months, but it’s best to cook the pasta fresh when you're ready to serve. Freeze the broth, vegetables, herbs, and chicken in a container without the pasta. When thawed, simply prepare some fresh pastina and add it during reheating for the best texture and flavor.

Reheating

Reheat the soup gently over low to medium heat on the stove, stirring occasionally to prevent sticking. If it’s too thick, loosen it up with a bit of extra broth or water. Avoid microwave reheating if possible, as gentle stovetop warming preserves the soup’s silky texture better and keeps the flavors bright.

FAQs

Can I use homemade chicken broth instead of store-bought?

Absolutely! Homemade chicken broth will add an extra depth of flavor and a personal touch to this Italian Penicillin Soup Recipe. Just be mindful of salt levels if your broth is especially concentrated.

Is pastina the only pasta that works in this soup?

While pastina is traditional and ideal for its tiny size and delicate texture, you can substitute small pasta shapes like orzo or acini di pepe. Just adjust cooking times accordingly to prevent overcooking.

Can I make this soup vegetarian?

To create a vegetarian version, replace the chicken broth with a rich vegetable broth and omit the chicken. Add extra vegetables or beans for protein and heartiness without losing the comforting feel.

What’s the purpose of using the Parmigiano-Reggiano rind?

The cheese rind imparts a deep, savory umami flavor to the broth as it simmers, enhancing richness without adding dairy heaviness. It’s a fantastic way to extract maximum taste from Parmesan while reducing waste.

How can I make this soup spicier?

To add a gentle kick, try incorporating a pinch of red pepper flakes during simmering or drizzle some chili oil when serving. Both will complement the soup’s savory base without overpowering its harmony.

Final Thoughts

There you have it — a soul-warming Italian Penicillin Soup Recipe that’s sure to become a cherished favorite in your kitchen. It takes simple ingredients and transforms them into a dish bursting with comforting flavor, creamy texture, and just the right dose of comforting familiarity. Invite friends and family to share this treat, and you might just find yourself making it again and again. Trust me, once you taste this soup, there’s no going back to ordinary chicken noodle soups.

Italian Penicillin Soup Recipe

Ingredients You'll Need

How to Make Italian Penicillin Soup Recipe